rs5742909

plus

Geno	Mag	Summary
(C;C)	0

Make rs5742909(C;T)

Make rs5742909(T;T)

Reference

GRCh38 38.1/141

Chromosome

2

Position

203867624

Gene

CTLA4

is a	snp
is	mentioned by
dbSNP	rs5742909
dbSNP (classic)	rs5742909
ClinGen	rs5742909
ebi	rs5742909
HLI	rs5742909
Exac	rs5742909
Gnomad	rs5742909
Varsome	rs5742909
LitVar	rs5742909
Map	rs5742909
PheGenI	rs5742909
Biobank	rs5742909
1000 genomes	rs5742909
hgdp	rs5742909
ensembl	rs5742909
geneview	rs5742909
scholar	rs5742909
google	rs5742909
pharmgkb	rs5742909
gwascentral	rs5742909
openSNP	rs5742909
23andMe	rs5742909
SNPshot	rs5742909
SNPdbe	rs5742909
MSV3d	rs5742909
GWAS Ctlg	rs5742909

GMAF

0.07346

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 19619703 ] Association of genetic variants with the metabolic syndrome in 20,806 white women: The women's health genome study

[PMID 21040781] CTLA-4 confers a risk of recurrent schizophrenia, major depressive disorder and bipolar disorder in the Chinese Han population

[PMID 21513760] Association of CTLA4 gene polymorphisms with lymphatic filariasis in an East Malaysian population

[PMID 15452244 ] Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection.

[PMID 15726497 ] Gene-environment interaction effects on the development of immune responses in the 1st year of life.

[PMID 17683561 ] The TCF7L2 locus and type 1 diabetes.

[PMID 17697348 ] Technology to accelerate pangenomic scanning for unknown point mutations in exonic sequences: cycling temperature capillary electrophoresis (CTCE).

[PMID 17825114 ] Association of CTLA-4 gene polymorphisms with sporadic breast cancer in Chinese Han population.

[PMID 18528295 ] Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade.

[PMID 18556337 ] Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).

[PMID 18576317 ] Lack of association of functional CTLA4 polymorphisms with juvenile idiopathic arthritis.

[PMID 18773895 ] The genetic basis of primary biliary cirrhosis: premises, not promises.

[PMID 18778710 ] Primary biliary cirrhosis is associated with a genetic variant in the 3' flanking region of the CTLA4 gene.

[PMID 19014504 ] Lack of association between sCTLA-4 levels in human plasma and common CTLA-4 polymorphisms.

[PMID 19131662 ] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.

[PMID 19180256 ] Genotype analysis of polymorphisms in autoimmune susceptibility genes, CTLA-4 and PTPN22, in an acute anterior uveitis cohort.

[PMID 19263529 ] Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.

[PMID 19330901 ] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.

[PMID 19500380 ] LD2SNPing: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs.

[PMID 19559392 ] A candidate gene association study of 77 polymorphisms in migraine.

[PMID 19622768 ] CTLA4 variants, UV-induced tolerance, and risk of non-melanoma skin cancer.

[PMID 19672595 ] Polymorphisms in the CD28/CTLA4/ICOS genes: role in malignant melanoma susceptibility and prognosis?

[PMID 19735686] CTLA-4 promoter polymorphisms are associated with latent autoimmune diabetes in adults.

[PMID 19740340 ] The CTLA-4 gene polymorphisms are associated with CTLA-4 protein expression levels in multiple sclerosis patients and with susceptibility to disease.

[PMID 19956097 ] Remapping the type I diabetes association of the CTLA4 locus.

[PMID 19956101 ] Overview of the Rapid Response data.

[PMID 20537165 ] The CTLA4 variants may interact with the IL23R- and NOD2-conferred risk in development of Crohn's disease.

[PMID 20557968] Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients.

[PMID 20610662 ] Association of single nucleotide polymorphisms in cytotoxic T-lymphocyte antigen 4 and susceptibility to autoimmune type 1 diabetes in Tunisians.

[PMID 20732370] CTLA4 and CD86 gene polymorphisms and susceptibility to chronic obstructive pulmonary disease.

[PMID 21644231] [Single nucleotide polymorphisms of CTLA4 gene and their association with human cervical cancer].

[PMID 21669243] CTLA-4, CD28, and ICOS gene polymorphism associations with non-small-cell lung cancer.

[PMID 22414241] Cytotoxic T-lymphocyte associated antigen-4 gene polymorphisms and primary biliary cirrhosis: A systematic review.

[PMID 22418270] Polymorphisms in cytotoxic T lymphocyte associated antigen-4 influence the rate of acute rejection after renal transplantation in 167 Chinese recipients.

[PMID 23432218] Association between cytotoxic T-lymphocyte antigen 4 gene polymorphisms and primary biliary cirrhosis in Chinese population: data from a multicenter study

[PMID 23480667] Cytotoxic T-Lymphocyte Antigen-4 Genetic Variants and Risk of Ewing's Sarcoma

[PMID 23597029 ] The associations between the polymorphisms in the CTLA-4 gene and the risk of Graves' disease in the Chinese population

[PMID 23661460] CTLA-4 and CD86 genetic variants and haplotypes in patients with rheumatoid arthritis in southeastern China

[PMID 23703660] The -319C/+49G/CT60G Haplotype of CTLA-4 Gene Confers Susceptibility to Rheumatoid Arthritis in Mexican Population

[PMID 23830732] CTLA-4 gene polymorphism at position +49 A>G in exon 1: a risk factor for cervical cancer in Indian women

[PMID 24270470] Influence of cytotoxic T lymphocyte-associated antigen 4 polymorphisms on the outcomes of hepatitis B virus infection

[PMID 24298899] Investigation of CTLA-4 and CD86 gene polymorphisms in a group of Iranian patients with brucellosis infection

[PMID 24313821] Association of CTLA-4 Gene Polymorphism with End-Stage Renal Disease and Renal Allograft Outcome

[PMID 24385694 ] Effect of cytotoxic T-lymphocyte antigen-4, TNF-alpha polymorphisms on osteosarcoma: evidences from a meta-analysis

[PMID 22905924] Cytotoxic T-lymphocyte antigen-4 polymorphisms and susceptibility to Ewing's sarcoma.

[PMID 22928528] Expression of genes involved in susceptibility to multifactorial autoimmune diseases: estimating genotype effects.

[PMID 23010350] Lack of association between CTLA-4 +49A/G and -318C/T polymorphisms and Behcet's disease risk: a meta-analysis.

[PMID 23133602 ] Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants.

[PMID 23261408] -1722T/C polymorphism (rs733618) of CTLA-4 significantly associated with systemic lupus erythematosus (SLE): a comprehensive meta-analysis.

[PMID 25645050] Association between the CTLA-4, CD226, FAS polymorphisms and rheumatoid arthritis susceptibility: A meta-analysis

[PMID 26079279] HCV F protein amplifies the predictions of IL-28B and CTLA-4 polymorphisms about the susceptibility and outcomes of HCV infection in Southeast China

[PMID 26403483] CTLA-4 and CD28 genes' polymorphisms and renal cell carcinoma susceptibility in the Polish population - a prospective study

[PMID 29264740] CTLA-4 polymorphisms are associated with treatment outcomes of patients with multiple myeloma receiving bortezomib-based regimens.

[PMID 29794444] Association of Five Snps in Cytotoxic T-Lymphocyte Antigen 4 and Cancer Susceptibility: Evidence from 67 Studies.

[PMID 30223781 ] Correlation between CTLA-4 and CD40 gene polymorphisms and their interaction in graves' disease in a Chinese Han population.

[PMID 31883177] Association of cytotoxic T-lymphocyte associated protein 4 gene polymorphisms with the risk and prognosis of oesophageal cancer in a high-incidence region from northern China.

[PMID 32148371 ] Single-nucleotide Polymorphism of CTLA-4 (rs5742909) in Correlation with Schizophrenia Risk Factor.