|(A;G)||0.6x decreased risk for diabetic nephropathy in females with type-1 diabetes; 1.9x increased malaria risk|
|(G;G)||0.6x decreased risk for diabetic nephropathy in females with type-1 diabetes; 1.9x increased malaria risk|
In a study of the type-1 diabetes complication known as diabetic nephropathy (DN), 662 (312 female/350 male) T1D patients with DN and 620 (369/251) without DN were studied (all were Swedish Caucasians). The rs5498(G) allele was found to be significantly associated with decreased risk for diabetic nephropathy specifically in female T1D patients, with an odds ratio of 0.692 (CI: 0.5-0.958, p= 0.010).10.1186/1471-2350-9-47
|95% CI||NR) umol/L increas|
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|Odds Ratio||13.8000 [NR] ng/mL increase|
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|qualified_impact||Insufficiently evaluated pharmacogenetic|
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