|(C;C)||0.29x lower risk for periodontitis|
|(C;T)||0.29x lower risk for periodontitis|
May modulate other variations. Also known as the +2018T/C SNP.
IL1B -511 allele heterozygotes have a 4 fold higher chance of surviving bacterial meningitis than (either) homozygote [PMID 11023482]. SO what's this have to do with rs419598? Odds of surviving meningitis apparently further increase 2X for IL1B -511 heterozygotes who are also rs419598(T;T), i.e. homozygous for IL1RN +2018 rs419598 (T) allele (the most common one; also known as "+8006").
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|Disease||Interleukin 1 receptor antagonist deficiency not specified|
|CLNDBN||Interleukin 1 receptor antagonist deficiency not specified|
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