rs397516436

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(C;C)	0	common in clinvar
(C;T)	7	Li-Fraumeni Syndrome (predicted)

Make rs397516436(T;T)

Reference

GRCh38 38.1/141

Chromosome

17

Position

7674894

Gene

TP53

is a	snp
is	mentioned by
dbSNP	rs397516436
dbSNP (classic)	rs397516436
ClinGen	rs397516436
ebi	rs397516436
HLI	rs397516436
Exac	rs397516436
Gnomad	rs397516436
Varsome	rs397516436
LitVar	rs397516436
Map	rs397516436
PheGenI	rs397516436
Biobank	rs397516436
1000 genomes	rs397516436
hgdp	rs397516436
ensembl	rs397516436
geneview	rs397516436
scholar	rs397516436
google	rs397516436
pharmgkb	rs397516436
gwascentral	rs397516436
openSNP	rs397516436
23andMe	rs397516436
SNPshot	rs397516436
SNPdbe	rs397516436
MSV3d	rs397516436
GWAS Ctlg	rs397516436

Max Magnitude

0

ClinVar
Risk	rs397516436(G;G) rs397516436(T;T)
Alt	rs397516436(G;G) rs397516436(T;T)
Reference	Rs397516436(C;C)
Significance	Pathogenic
Disease	Li-Fraumeni syndrome Hereditary cancer-predisposing syndrome Li-Fraumeni syndrome 1 not provided Hepatocellular carcinoma Malignant neoplasm of body of uterus Glioblastoma Malignant melanoma of skin Squamous cell carcinoma of the head and neck Oesophageal carcinoma Colorectal Neoplasms Adenoid cystic carcinoma Pancreatic adenocarcinoma Renal cell carcinoma Adrenocortical carcinoma Neoplasm of brain Ovarian Serous Cystadenocarcinoma Adenocarcinoma of stomach Squamous cell carcinoma of the skin Transitional cell carcinoma of the bladder Nasopharyngeal Neoplasms Uterine Carcinosarcoma Adenocarcinoma of prostate Squamous cell carcinoma of lung Adenocarcinoma of lung Neoplasm of breast
Variation	info
Gene	TP53
CLNDBN	Li-Fraumeni syndrome Hereditary cancer-predisposing syndrome Li-Fraumeni syndrome 1 not provided Hepatocellular carcinoma Malignant neoplasm of body of uterus Glioblastoma Malignant melanoma of skin Squamous cell carcinoma of the head and neck Oesophageal carcinoma Colorectal Neoplasms Adenoid cystic carcinoma Pancreatic adenocarcinoma Renal cell carcinoma Adrenocortical carcinoma Neoplasm of brain Ovarian Serous Cystadenocarcinoma Adenocarcinoma of stomach Squamous cell carcinoma of the skin Transitional cell carcinoma of the bladder Nasopharyngeal Neoplasms Uterine Carcinosarcoma Adenocarcinoma of prostate Squamous cell carcinoma of lung Adenocarcinoma of lung Neoplasm of breast
Reversed	1
HGVS	NC_000017.10:g.7578212G>A; NC_000017.10:g.7578212G>C
CLNSRC	COSMIC
CLNACC	RCV000036532.5, RCV000115730.7, RCV000144672.3, RCV000213050.2, RCV000417479.1, RCV000419627.1, RCV000420272.1, RCV000421524.1, RCV000421648.1, RCV000424254.1, RCV000425630.1, RCV000426157.1, RCV000426799.1, RCV000428146.1, RCV000428823.1, RCV000430949.1, RCV000431481.1, RCV000432206.1, RCV000432863.1, RCV000436862.1, RCV000437472.1, RCV000438186.1, RCV000438677.1, RCV000438834.1, RCV000444193.1, RCV000444980.1,