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From SNPedia

Geno Mag Summary
(C;C) 0 common in clinvar
Make rs3856806(C;T)
Make rs3856806(T;T)
ReferenceGRCh38 38.1/141
is asnp
is mentioned by
dbSNP (classic)rs3856806
1000 genomesrs3856806
GWAS Ctlgrs3856806
Max Magnitude0
? (C;C) (C;T) (T;T) 28

[PMID 20596649] PPARgamma polymorphisms and cancer risk: A meta-analysis involving 32,138 subjects

[PMID 21263402] Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes

[PMID 21284483] Genetic Variants in Peroxisome Proliferator-Activated Receptor-? and Retinoid X Receptor-? Gene and Type 2 Diabetes Risk: A Case-Control Study of a Chinese Han Population


[PMID 22475777] Association Between PPAR-? and RXR-? Gene Polymorphism and Metabolic Syndrome Risk: A Case-Control Study of a Chinese Han Population

Risk rs3856806(T;T)
Alt rs3856806(T;T)
Reference Rs3856806(C;C)
Significance Probable-non-pathogenic
Disease Glioma susceptibility 1 not specified Diabetes Mellitus Familial partial lipodystrophy Obesity
Variation info
CLNDBN Glioma susceptibility 1 not specified Diabetes Mellitus, Noninsulin-Dependent, with Acanthosis Nigricans and Hypertension Familial partial lipodystrophy Obesity
Reversed 0
HGVS NC_000003.11:g.12475557C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000008615.3, RCV000118043.2, RCV000276900.1, RCV000331945.1, RCV000371595.1,

[PMID 16713673] Variations in the peroxisome proliferator-activated receptor-gamma gene and melanoma risk.

[PMID 16783862] PPAR-gamma gene polymorphisms and psoriatic arthritis.

[PMID 17347532OA-icon.png] The Genetics of PPARG and the Skeleton.

[PMID 18160840] The association of Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma gene with serum osteoprotegerin levels in healthy Korean women.

[PMID 18340007OA-icon.png] Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia.

[PMID 18375961OA-icon.png] Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China.

[PMID 18401448OA-icon.png] PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease.

[PMID 18426866OA-icon.png] Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort.

[PMID 18454203OA-icon.png] Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression.

[PMID 18603647OA-icon.png] Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.

[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.

[PMID 18707223OA-icon.png] PPARG by dietary fat interaction influences bone mass in mice and humans.

[PMID 18805939OA-icon.png] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.

[PMID 18992148OA-icon.png] Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

[PMID 19002430] Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population.

[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.

[PMID 19208777] Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.

[PMID 19223982OA-icon.png] Genetic Variability of RXRB, PPARA, and PPARG in Wegener's Granulomatosis.

[PMID 20426853OA-icon.png] Association and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic function.

[PMID 21140205] Joint effect of peroxisome proliferator-activated receptor gamma genetic polymorphisms and estrogen-related risk factors on breast cancer risk: results from a case-control study in Taiwan.

[PMID 21252350] Variants of the human PPARG locus and the susceptibility to chronic periodontitis.

[PMID 21756892] PPARG gene promoter polymorphism is associated with non-traumatic hip fracture risk in the elderly Slovenian population: a pilot study.

[PMID 22023374OA-icon.png] Application of back propagation artificial neural network on genetic variants in adiponectin ADIPOQ, peroxisome proliferator-activated receptor-gamma, and retinoid X receptor-alpha genes and type 2 diabetes risk in a Chinese Han population.

[PMID 22410809] Association of PPAR-gamma gene polymorphisms with obesity and obesity-associated phenotypes in north indian population.

[PMID 22968028] [Association of both peroxisome proliferator-activated receptor, gene-gene interactions and the body mass index]

[PMID 23262340] Gene-gene interactions among PPARα/δ/γ polymorphisms for hypertriglyceridemia in Chinese Han population

[PMID 23741228OA-icon.png] Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia

[PMID 23545576OA-icon.png] Association of peroxisome proliferator-activated receptor α/δ/γ with obesity, and gene-gene interaction, in the Chinese Han population

[PMID 23907334OA-icon.png] Genetic Variants of Peroxisome Proliferator-Activated Receptor δ Are Associated with Gastric Cancer

[PMID 23937834] [Effects related to gene-gene interactions of peroxisome proliferator-activated receptor on essential hypertension]

[PMID 23363867] [Gene-gene interactions among the peroxisome proliferator-activated receptor polymorphisms for hypertriglyceridemia]

[PMID 22537818] Polymorphisms in adiposity-related genes are associated with age at menarche and menopause in breast cancer patients and healthy women.

[PMID 22987045] The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease.

[PMID 23533563OA-icon.png] Novel risk factors for premature peripheral arterial occlusive disease in non-diabetic patients: a case-control study.

[PMID 25274455] The gene polymorphisms of UCP1 but not PPAR γ and TCF7L2 are associated with diabetic retinopathy in Chinese type 2 diabetes mellitus cases

[PMID 25832497] Association between Peroxisome Proliferator-activated Receptor Gamma Gene Polymorphisms and Atherosclerotic Diseases: A Meta-analysis of Case-control Studies

[PMID 26110145OA-icon.png] Gene-Gene Interactions among Pparα/δ/γ Polymorphisms for Apolipoprotein (Apo) A-I/Apob Ratio in Chinese Han Population

[PMID 25422184] Lack of effects of peroxisome proliferator-activated receptor gamma genetic polymorphisms on breast cancer risk: a case-control study and pooled analysis

[PMID 26268872] [Association and interaction between 10 SNP of peroxisome proliferator-activated receptor and non-HDL-C]

[PMID 26550133OA-icon.png] Peroxisome proliferator-activated receptor gamma (PPARG) polymorphisms and breast cancer susceptibility: a meta-analysis

[PMID 24599720] Effect of obesity on the association between common variations in the PPAR gene and C-reactive protein level in Chinese Han population

[PMID 26885119OA-icon.png] Interaction between peroxisome proliferator- activated receptor gamma polymorphism and overweight on diabetic retinopathy in a Chinese case-control study.

[PMID 28123453OA-icon.png] Interaction between peroxisome proliferator-activated receptor gamma polymorphism and obesity on type 2 diabetes in a Chinese Han population.

[PMID 31915541OA-icon.png] PPARG Polymorphisms Are Associated with Unexplained Mild Vision Loss in Patients with Type 2 Diabetes Mellitus.