rs3812316
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common on affy axiom data |
| Make rs3812316(C;G) |
| Make rs3812316(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 73606007 |
| Gene | MLXIPL |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3812316 |
| dbSNP (classic) | rs3812316 |
| ClinGen | rs3812316 |
| ebi | rs3812316 |
| HLI | rs3812316 |
| Exac | rs3812316 |
| Gnomad | rs3812316 |
| Varsome | rs3812316 |
| LitVar | rs3812316 |
| Map | rs3812316 |
| PheGenI | rs3812316 |
| Biobank | rs3812316 |
| 1000 genomes | rs3812316 |
| hgdp | rs3812316 |
| ensembl | rs3812316 |
| geneview | rs3812316 |
| scholar | rs3812316 |
| rs3812316 | |
| pharmgkb | rs3812316 |
| gwascentral | rs3812316 |
| openSNP | rs3812316 |
| 23andMe | rs3812316 |
| SNPshot | rs3812316 |
| SNPdbe | rs3812316 |
| MSV3d | rs3812316 |
| GWAS Ctlg | rs3812316 |
| GMAF | 0.08632 |
| Max Magnitude | 0 |
rs3812316, a SNP in the MLXIPL gene that is also known as G771C or Gln241His, has been observed in a study of over 10,000 individuals of different ethnicities to be very significantly associated (p=1.4x10e-10) with plasma triglyceride levels.[PMID 18193046]
| GWAS | |
|---|---|
| SNP | rs3812316 |
| PubMedID | [PMID 18193046] |
| Condition | Triglycerides |
| Gene | MLXIPL |
| Risk Allele | C |
| pValue | 1.00E-010 |
| OR | 10.5 |
| 95% CI | 5.3-17.7)% highe |
[PMID 19571538] G771C Polymorphism in the MLXIPL Gene Is Associated with a Risk of Coronary Artery Disease in the Chinese: A Case-Control Study
[PMID 19487539] Large scale replication analysis of loci associated with lipid concentrations in a Japanese population
[PMID 19680233] Replication of Association Between a Common Variant Near Melanocortin-4 Receptor Gene and Obesity-related Traits in Asian Sikhs
[PMID 21726544] ChREBP gene polymorphisms are associated with coronary artery disease in Han population of Hubei province
[PMID 18852197
] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 18946681] MLXIPL variant in individuals with low and high triglyceridemia in white population in Central Europe.
[PMID 20158509] Triglyceride level modifying functional variants of GALTN2 and MLXIPL in patients with ischaemic stroke.
[PMID 24448738] An Amino Acid Change in the Carbohydrate Response Element Binding Protein is Associated with Lower Triglycerides and Myocardial Infarction Incidence Depending on Level of Adherence to the Mediterranean Diet in the PREDIMED Trial
[PMID 24989072] Association between the MLX interacting protein-like, BUD13 homolog and zinc finger protein 259 gene polymorphisms and serum lipid levels
[PMID 27854512] Genetic and Environmental Biomarkers Associated with Triglyceride Levels in Two Groups of Slovak Women.
[PMID 31268920] Association of the ESR1 polymorphism with menopause and MLXIPL genetic variant influence serum uric acid levels in Slovak midlife women.
