|| slight increase in child-onset mood disorder
The very common allele of rs35369693
was observed to be associated with child-onset mood disorders (primarily depression
or bipolar disorder
) based on transmission disequilibrium testing of 382 Hungarian families. The association is predominantly noticed only in affected females. This SNP represents a variation at amino acid 65 of the AVPR1B
[PMID 24842238] Association between a polymorphism of the vasopressin 1B receptor gene and aggression in children. Study finds a significant relationship between the minor C allele on rs35369693 and childhood aggression.