rs276174825

plus

Geno	Mag	Summary
(-;CT)	6	BRCA2 variant considered pathogenic for breast cancer
(CT;CT)	0	common in clinvar

Make rs276174825(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32319271

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs276174825
dbSNP (classic)	rs276174825
ClinGen	rs276174825
ebi	rs276174825
HLI	rs276174825
Exac	rs276174825
Gnomad	rs276174825
Varsome	rs276174825
LitVar	rs276174825
Map	rs276174825
PheGenI	rs276174825
Biobank	rs276174825
1000 genomes	rs276174825
hgdp	rs276174825
ensembl	rs276174825
geneview	rs276174825
scholar	rs276174825
google	rs276174825
pharmgkb	rs276174825
gwascentral	rs276174825
openSNP	rs276174825
23andMe	rs276174825
SNPshot	rs276174825
SNPdbe	rs276174825
MSV3d	rs276174825
GWAS Ctlg	rs276174825

Max Magnitude

6

rs276174825, also known as 490delCT, c.262_263delCT and p.Leu88Alafs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

Note: the 23andMe probe (i5009247) corresponding to this genotype is unreliable (prone to false results).

ClinVar
Risk	rs276174825(-;-)
Alt	rs276174825(-;-)
Reference	Rs276174825(CT;CT)
Significance	Pathogenic
Disease	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA2
CLNDBN	Hereditary breast and ovarian cancer syndrome Breast-ovarian cancer, familial 2 Hereditary cancer-predisposing syndrome
Reversed	0
HGVS	NC_000013.10:g.32893408_32893409delCT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000044028.3, RCV000113331.5, RCV000162895.1,