rs276174814

Merged into

rs276174813

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(-;CTTAT)	6	BRCA2 variant considered pathogenic for breast cancer
(-;TTTAT)	6	BRCA2 variant considered pathogenic for breast cancer
(ATCTT;ATCTT)	0	common in clinvar
(CTTAT;CTTAT)	0	common in clinvar

Make rs276174814(-;-)

Reference

GRCh38 38.1/141

Chromosome

13

Position

32333274

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs276174814
ClinGen	rs276174814
ebi	rs276174814
HLI	rs276174814
Exac	rs276174814
Varsome	rs276174814
Map	rs276174814
PheGenI	rs276174814
hapmap	rs276174814
1000 genomes	rs276174814
hgdp	rs276174814
ensembl	rs276174814
gopubmed	rs276174814
geneview	rs276174814
scholar	rs276174814
google	rs276174814
pharmgkb	rs276174814
gwascentral	rs276174814
openSNP	rs276174814
23andMe	rs276174814
23andMe all	rs276174814
SNP Nexus
SNPshot	rs276174814
SNPdbe	rs276174814
MSV3d	rs276174814
GWAS Ctlg	rs276174814

Status

Merged into rs276174813

Max Magnitude

6

rs276174814, also known as 2024del5, c.1796_1800delTTTAT and p.Ser599_Tyr600?fs, is a variant in the BRCA2 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs276174814(ATCTT;ATCTT)
Significance	Pathogenic
Disease	Breast-ovarian cancer not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 not provided Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32907411_32907415delCTTAT
CLNSRC	Breast Cancer Information Core (BRCA2)
CLNACC	RCV000031337.7, RCV000043887.5, RCV000129987.3, RCV000168232.3,