rs273898676

minus

Geno	Mag	Summary
(-;AA)	6	BRCA1 variant considered pathogenic for breast cancer
(AA;AA)	0	common in clinvar

Make rs273898676(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43093460

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs273898676
dbSNP (classic)	rs273898676
ClinGen	rs273898676
ebi	rs273898676
HLI	rs273898676
Exac	rs273898676
Gnomad	rs273898676
Varsome	rs273898676
LitVar	rs273898676
Map	rs273898676
PheGenI	rs273898676
Biobank	rs273898676
1000 genomes	rs273898676
hgdp	rs273898676
ensembl	rs273898676
geneview	rs273898676
scholar	rs273898676
google	rs273898676
pharmgkb	rs273898676
gwascentral	rs273898676
openSNP	rs273898676
23andMe	rs273898676
SNPshot	rs273898676
SNPdbe	rs273898676
MSV3d	rs273898676
GWAS Ctlg	rs273898676

Max Magnitude

6

rs273898676, also known as 2189delAA, c.2070_2071delAA and p.Lys690_Arg691LysThrfs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs273898676(-;-)
Alt	rs273898676(-;-)
Reference	Rs273898676(AA;AA)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1 Hereditary cancer-predisposing syndrome
Reversed	1
HGVS	NC_000017.10:g.41245477_41245478delTT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000077091.3, RCV000162849.2,