rs273897665

minus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;A)	6	BRCA1 variant considered pathogenic for breast cancer

Make rs273897665(A;A)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43106478

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs273897665
ClinGen	rs273897665
ebi	rs273897665
HLI	rs273897665
Exac	rs273897665
Varsome	rs273897665
Map	rs273897665
PheGenI	rs273897665
hapmap	rs273897665
1000 genomes	rs273897665
hgdp	rs273897665
ensembl	rs273897665
gopubmed	rs273897665
geneview	rs273897665
scholar	rs273897665
google	rs273897665
pharmgkb	rs273897665
gwascentral	rs273897665
openSNP	rs273897665
23andMe	rs273897665
23andMe all	rs273897665
SNP Nexus
SNPshot	rs273897665
SNPdbe	rs273897665
MSV3d	rs273897665
GWAS Ctlg	rs273897665

Max Magnitude

6

rs273897665, also known as 308insA, c.189_190insA and p.Leu63_Cys64?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs273897665(A;A)
Alt	rs273897665(A;A)
Reference	Rs273897665(-;-)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41258496dupT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047629.2, RCV000111973.2,