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rs2630578

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in complete genomics
Make rs2630578(C;C)
Make rs2630578(C;G)
ReferenceGRCh38 38.1/141
Chromosome12
Position32152853
GeneBICD1
is asnp
is mentioned by
dbSNPrs2630578
dbSNP (old)rs2630578
ClinGenrs2630578
ebirs2630578
HLIrs2630578
Exacrs2630578
Gnomadrs2630578
Varsomers2630578
Maprs2630578
PheGenIrs2630578
Biobankrs2630578
1000 genomesrs2630578
hgdprs2630578
ensemblrs2630578
gopubmedrs2630578
geneviewrs2630578
scholarrs2630578
googlers2630578
pharmgkbrs2630578
gwascentralrs2630578
openSNPrs2630578
23andMers2630578
23andMe allrs2630578
SNP Nexus

SNPshotrs2630578
SNPdbers2630578
MSV3drs2630578
GWAS Ctlgrs2630578
GMAF0.1483
Max Magnitude0
? (C;C) (C;G) (G;G) 28
[PMID 18487243] An association regarding telomere length with a p-value of (1.9x10^(-5)), stated that people carrying the minor allele 'C' at rs2630578 have telomeres within their white blood cells (leukocytes) that are on average 604 (+/-204) base pairs shorter than people who carry the common 'GG' genotype at this SNP. The authors estimate that this size of a difference between telomere length is equivalent to having cells which have comparatively gone through an additional "15-20 years of age-related attrition", however, no actual effects on aging or health were associated with this SNP in the study.


As rs2630578 was genotyped by both the v3 & v4 chips, it should be in 23andMe's database for the majority of their customers, however, if this specific location was not genotyped or returned a 'No Call' or similar non-result—it may still be possible to determine your genotype by using the direct substitute rs2668301. This is possible because, as made apparent by comparing the population frequencies of the two SNPs, they are in very close linkage with one another within most human populations. Meaning, the 'T' version of rs2668301 is equivalent to having the 'G' version of rs2630578, and the 'C' alleles for both SNPs are equivalent to each other.)


[PMID 20127402OA-icon.png] Cerebellar telomere length and psychiatric disorders

OMIM609113
Desc
Variant
Relatedalso
[PMID 22314626] Genetic variants implicated in telomere length associated with left ventricular function in patients with hypertension and cardiac organ damage


[PMID 24349443OA-icon.png] Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease


[PMID 25792135] hTERT, BICD1 and Chromosome 18 Polymorphisms Associated with Telomere Length Affect Kidney Allograft Function After Transplantation