|| common in complete genomics
|?|| (C;C) (C;T) (T;T) ||28|
rs2302685 increases susceptibility to Alzheimer's disease, late-onset 1.30 times for carriers of the T allele [PMID 17517621]
[PMID 22393312] Association of a Functional Variant in the Wnt Co-Receptor LRP6 with Early Onset Ileal Crohn's Disease
[PMID 18340469] Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease.
[PMID 19667113] A common variant in low-density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol.
[PMID 20057906] Mutational screening of 10 genes in Chinese patients with microphthalmia and/or coloboma.
[PMID 20926594] Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication.
|| not reviewed
|| Insufficiently evaluated not reviewed
[PMID 24906453] The LRP6 rs2302685 polymorphism is associated with increased risk of myocardial infarction