|Less likely to suffer from vitamin D insufficiency|
|(A;C)||1||somewhat lower vitamin D levels|
|(C;C)||1.5||lower vitamin D levels|
In both studies, the allele associated with lower vitamin D, and thus the potential for vitamin D insufficiency, is rs2282679(C). Carriers of two such alleles have lower vitamin D than carriers of one allele, who in turn on average have lower vitamin D levels than rs2282679(A;A) individuals.10.1016/S0140-6736(10)60588-0
|Trait||Vitamin D levels|
|Title||Genome-wide association study of circulating vitamin D levels|
|Odds Ratio||0.38 [0.32-0.44] unit decrease|
|Trait||Vitamin D insufficiency|
|Title||Common genetic determinants of vitamin D insufficiency: a genome-wide association study.|
|Odds Ratio||None None|
[PMID 19255064] Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.
[PMID 21972121] Associations between common variants in GC and DHCR7/NADSYN1 and vitamin D concentration in Chinese Hans.
[PMID 22613962] Genetic Influences on Vitamin D Status and Forearm Fracture Risk in African American Children.
|Title||Genome-wide association analysis of circulating vitamin D levels in children with asthma.|
|Odds Ratio||None None|
[PMID 22704802] Vitamin D-binding protein (group-specific component) has decreased expression in rheumatoid arthritis
[PMID 22701574] Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
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[PMID 28161065] Placental genetic variations in vitamin D metabolism and birthweight.
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