rs2242480
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | normal |
| (C;T) | carrier of one CYP3A4*_20239G>A allele | |
| (T;T) | CYP3A4*_20239G>A homozygote |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 99763843 |
| Gene | CYP3A4 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2242480 |
| dbSNP (classic) | rs2242480 |
| ClinGen | rs2242480 |
| ebi | rs2242480 |
| HLI | rs2242480 |
| Exac | rs2242480 |
| Gnomad | rs2242480 |
| Varsome | rs2242480 |
| LitVar | rs2242480 |
| Map | rs2242480 |
| PheGenI | rs2242480 |
| Biobank | rs2242480 |
| 1000 genomes | rs2242480 |
| hgdp | rs2242480 |
| ensembl | rs2242480 |
| geneview | rs2242480 |
| scholar | rs2242480 |
| rs2242480 | |
| pharmgkb | rs2242480 |
| gwascentral | rs2242480 |
| openSNP | rs2242480 |
| 23andMe | rs2242480 |
| SNPshot | rs2242480 |
| SNPdbe | rs2242480 |
| MSV3d | rs2242480 |
| GWAS Ctlg | rs2242480 |
| GMAF | 0.3338 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2242480 is a SNP in the CYP3A4 gene.
The rs2242480(T) allele defines the CYP3A4*_20239G>A variant.
[PMID 21692828
] The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors
[PMID 21902501] Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients
[PMID 17615053] Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.
[PMID 18163429] Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.
[PMID 18504423] Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response.
[PMID 18825162] Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.
[PMID 21071160] Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.
[PMID 21199372] A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.
[PMID 22178823] [Distribution of variant alleles association with warfarin pharmacokinetics and pharmacodynamics in the Han population in China].
[PMID 22583563] Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore.
[PMID 25217544] Fatal Methadone Toxicity: Potential Role of CYP3A4 Genetic Polymorphism
[PMID 27257124] CYP gene family variants as a potential risk factors in drug addiction in Han Chinese.
[PMID 31874497] [Effect of opioid-related gene polymorphisms on patients with high-dose opioid-tolerant cancer pain].
