- rs2237895, P = 7.3 times 10-9; OR = 1.32, 95% CI = 1.20â€“1.45
[PMID 19366866] Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
[PMID 19448982] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China
[PMID 19516902] The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
[PMID 19575309] Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population
[PMID 19584308] A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
[PMID 19308350] Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
[PMID 19850681] Association of KCNQ1 Polymorphisms with the Gestational Diabetes Mellitus in Korean Women
|Trait||Type 2 diabetes|
|Title||A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese|
|Odds Ratio||1.29 [1.19-1.40]|
[PMID 22479571] Several Polymorphisms of KCNQ1 Gene Are Associated with Plasma Lipid Levels in General Chinese Populations
[PMID 22206064] KCNQ1 variants associate with type 2 diabetes in Malaysian Malay subjects
[PMID 18711366] SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
[PMID 19207020] Meta-analysis in genome-wide association studies.
[PMID 19252135] Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.
[PMID 19556355] Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.
[PMID 20606385] Polymorphisms in KCNQ1 are associated with gestational diabetes in a Korean population.
[PMID 20701788] KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population.
[PMID 21261977] Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US.
[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.
[PMID 21289621] Effects of KCNQ1 polymorphisms on the therapeutic efficacy of oral antidiabetic drugs in Chinese patients with type 2 diabetes.
[PMID 21291537] Evidence for somatic gene conversion and deletion in bipolar disorder, Crohn's disease, coronary artery disease, hypertension, rheumatoid arthritis, type-1 diabetes, and type-2 diabetes.
[PMID 21355884] KCNQ1 gene variants and risk of new-onset diabetes in tacrolimus-treated renal-transplanted patients.
[PMID 22414228] KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese Type 2 diabetic patients.
[PMID 22461567] Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.
[PMID 23133642] The Association between KCNQ1 Gene Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis
[PMID 23139357] Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets
[PMID 23271129] Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes
[PMID 23029294] Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus
[PMID 23786590] Common Variants in KCNQ1 Confer Increased Risk of Type 2 Diabetes and Contribute to the Diabetic Epidemic in East Asians: A Replication and Meta-Analysis
[PMID 22696034] KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes.
[PMID 22790062] Association between KCNQ1 genetic variants and obesity in Chinese patients with type 2 diabetes.
[PMID 23107108] Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs.
[PMID 23334806] Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus.
[PMID 23462794] Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
[PMID 23630301] Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.
[PMID 23692438] Association between KCNQ1 genetic variants and QT interval in a Chinese population.
[PMID 26109524] Role of high-risk variants in the development of impaired glucose metabolism was modified by birth weight in Han Chinese
[PMID 27155871] Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.
[PMID 28083030] KCNQ1 rs2237895 polymorphism is associated with Gestational Diabetes in Pakistani Women.
[PMID 28863213] Type 2 diabetes associated variants of KCNQ1 strongly confer the risk of cardiovascular disease among the Saudi Arabian population.