| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
common in complete genomics
|
per the 23andMe blog, the minor allele of this SNP (T) was associated with decreased HDL cholesterol
| GWAS snp
|
| PMID
|
[PMID 19060906 ]
|
| Trait
|
HDL cholesterol
|
| Title
|
Common variants at 30 loci contribute to polygenic dyslipidemia
|
| Risk Allele
|
T
|
| P-val
|
8E-10
|
| Odds Ratio
|
0.19 [0.09-0.29] SD decrease
|
[PMID 19748811] Influence of hepatocyte nuclear factor 4alpha (HNF4alpha) gene variants on the risk of type 2 diabetes: A meta-analysis in 49,577 individuals
| GWAS snp
|
| PMID
|
[PMID 21300955]
|
| Trait
|
|
| Title
|
Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels
|
| Risk Allele
|
C
|
| P-val
|
2E-9
|
| Odds Ratio
|
0.0880 [0.06-0.12] unit increase
|
| GWAS snp
|
| PMID
|
[PMID 20686565]
|
| Trait
|
|
| Title
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
| Risk Allele
|
T
|
| P-val
|
1E-15
|
| Odds Ratio
|
1.8800 None
|
[PMID 16186411] Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.
[PMID 18660489] Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.
[PMID 19915572] Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
[PMID 19951432] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
[PMID 20385826] Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).
| GWAS snp
|
| PMID
|
[PMID 22939635]
|
| Trait
|
C-reactive protein
|
| Title
|
Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.
|
| Risk Allele
|
T
|
| P-val
|
8E-6
|
| Odds Ratio
|
.27 [0.15-0.39] (unit decrease)
|
]
