|risk for prostate cancer|
|(A;A)||2.9||1.5x increased risk for prostate cancer|
|(A;C)||2.9||1.5x increased risk for prostate cancer|
In a study of over 3,600 Caucasians with prostate cancer, rs16901979 is one of five SNPs used (with family history as a sixth factor) to cumulatively predict overall risk. On their own, the rs16901979(A;A) and (A;C) risk genotypes yield an odds ratio for developing prostate cancer of 1.53 (CI: 1.22-1.92, p=1.8x10e-4) and may account for 3.6% of population attributable risk.10.1056/NEJMoa075819
cancer related according to this blog
|95% CI||1.53-2.11) (EA|
[PMID 19549807] Prostate Cancer Risk Associated Loci in African Americans
[PMID 19562729] Common variants in 8q24 are associated with risk for prostate cancer and tumor aggressiveness in men of European ancestry
|Title||Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility|
|Odds Ratio||1.80 [1.55-2.09]|
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