rs12188950

plus

Geno	Mag	Summary
(C;C)	0	common in complete genomics

Make rs12188950(C;T)

Make rs12188950(T;T)

Reference

GRCh38 38.1/141

Chromosome

5

Position

60487490

Gene	PART1, PDE4D

is a	snp
is	mentioned by
dbSNP	rs12188950
dbSNP (classic)	rs12188950
ClinGen	rs12188950
ebi	rs12188950
HLI	rs12188950
Exac	rs12188950
Gnomad	rs12188950
Varsome	rs12188950
LitVar	rs12188950
Map	rs12188950
PheGenI	rs12188950
Biobank	rs12188950
1000 genomes	rs12188950
hgdp	rs12188950
ensembl	rs12188950
geneview	rs12188950
scholar	rs12188950
google	rs12188950
pharmgkb	rs12188950
gwascentral	rs12188950
openSNP	rs12188950
23andMe	rs12188950
SNPshot	rs12188950
SNPdbe	rs12188950
MSV3d	rs12188950
GWAS Ctlg	rs12188950

GMAF

0.09229

Max Magnitude

0

In both a multi-site study including 2,500+ Swedish patients and a meta-analysis of 10,000+ patients in 17 publications, no association between rs12188950 and risk for ischemic stroke was found.

[PMID 22274584 ]

?

(C;C) (C;T) (T;T)

28

[PMID 16835261 ] Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.

[PMID 18398440] Ischaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region.

[PMID 19409523 ] Multilocus Bayesian meta-analysis of gene-disease associations.

[PMID 19426955 ] Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

[PMID 20540798 ] Sex-differential genetic effect of phosphodiesterase 4D (PDE4D) on carotid atherosclerosis.

[PMID 28191858] Impact of the PDE4D gene polymorphism and additional SNP-SNP and gene-smoking interaction on ischemic stroke risk in Chinese Han population.