rs10897346
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 3 | If depressed, 2.6x more likely to not respond to antidepressants |
| (C;T) | 3 | If depressed, 2.6x more likely to not respond to antidepressants |
| (T;T) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 55863349 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10897346 |
| dbSNP (classic) | rs10897346 |
| ClinGen | rs10897346 |
| ebi | rs10897346 |
| HLI | rs10897346 |
| Exac | rs10897346 |
| Gnomad | rs10897346 |
| Varsome | rs10897346 |
| LitVar | rs10897346 |
| Map | rs10897346 |
| PheGenI | rs10897346 |
| Biobank | rs10897346 |
| 1000 genomes | rs10897346 |
| hgdp | rs10897346 |
| ensembl | rs10897346 |
| geneview | rs10897346 |
| scholar | rs10897346 |
| rs10897346 | |
| pharmgkb | rs10897346 |
| gwascentral | rs10897346 |
| openSNP | rs10897346 |
| 23andMe | rs10897346 |
| SNPshot | rs10897346 |
| SNPdbe | rs10897346 |
| MSV3d | rs10897346 |
| GWAS Ctlg | rs10897346 |
| Max Magnitude | 3 |
Carriers of rs10897346(C) alleles showed a 2.6-fold increased risk (CI: 1.4-4.8) for nonresponse to all major types of anti-depressant drugs (such as the SSRI drug citalopram) in a study of 182 German patients.[PMID 18496129]
[PMID 21172166
] Pharmacogenetics of antidepressant response.
