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Intracranial Aneurysm

From SNPedia

A brain aneurysm, also called a cerebral or intracranial aneurysm, is an abnormal bulging outward of one of the arteries in the brain. www.brainaneurysm.com

[PMID 27895300] A paper published in late 2016 found rare heterozygous variants in the THDS1 gene associated with intracranial aneuryms and potentially therefore [https://en.wikipedia.org/wiki/Subarachnoid_hemorrhage subarachnoid hemorrhage} (i.e. a type of cerebral stroke). The variants found included:

rsid hg19 position Synonyms On chip?
13:52976721 c.15G>C, p.L5F
13:52952757 c.1348C>T, p.R450X
rs776400380 13:52952727 c.1378C>T, p.R460W
rs201805081 13:52952708 c.1397A>G, p.E466G
rs141140186 13:52952306 c.1799G>A, p.G600E
13:52952189 c.1916C>T, p.P639L
rs371717283 13:52952147 c.1958C>T, p.T635I
rs780150341 13:52951782 c.2323T>C, p.S775P