Have questions? Visit https://www.reddit.com/r/SNPedia

Genoset

From SNPedia
(Redirected from Genosets)

A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.

Promethease understands this criteria syntax.

More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.

Most Significant

 ReputeMagnitudeSummaryModification date"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
Gs14910Testing for orientation issues3 June 2017 01:13:36
Gs324Bad10Promethease is able to support this format, but we've identified this as coming from a vendor who's data is so error prone as to be worthless. This report is a correct representation of the data you gave us.3 September 2018 22:54:44
Gs318Bad10Unsupported platform9 April 2018 06:33:46
Gs3007Data Quality issue. Your data provider is reporting heterozygosity on the Y chromosome.23 October 2016 09:50:25
Gs3037WeGene quality control issues.8 June 2016 05:40:37
Gs306Bad6.5Poor metabolizer of fluoropyrimidines (e.g. 5-fluorouracil, capecitabine or tegafur).25 May 2017 00:56:35
Gs216Bad62 copies of the APOE-ε4 allele5 December 2017 19:38:24
Gs228Bad6Sickle cell affected3 June 2017 01:37:39
Gs2676APOE1/APOE15 November 2016 18:42:06
Gs314Bad6MUTYH-associated polyposis (and colon cancer risk)24 December 2017 19:56:29
... further results


Most Recently Active

 ReputeMagnitudeSummaryModification date"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
Gs1000Bad3.5causes gout28 March 2019 17:33:38
Gs186Bad1.5HLA-B*5801 heterozygosity is possible, unfortunately this is just too common to be useful24 March 2019 03:00:11
Gs310Good2.7Change in metabolism of certain substances22 March 2019 17:38:56
Gs311Bad2.7Slow metabolizer of certain substances22 March 2019 17:37:35
Gs328Bad3Celiac disease risk23 January 2019 21:10:07
Gs327Bad2.6Somewhat increased risk of Alzheimer's disease8 January 2019 00:10:14
Gs326Good3.8Reduced risk (0.15x) of breast cancer compared to average5 December 2018 22:51:04
Gs325Good3.1Reduced risk (0.64x) of breast cancer compared to average5 December 2018 22:37:01
Gs2802.2Light hair color for europeans18 November 2018 16:28:25
Gs324Bad10Promethease is able to support this format, but we've identified this as coming from a vendor who's data is so error prone as to be worthless. This report is a correct representation of the data you gave us.3 September 2018 22:54:44
... further results


You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.