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Genoset

From SNPedia

A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.

Promethease understands this criteria syntax.

More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.

Most Significant

 ReputeMagnitudeSummaryModification date
"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
Gs14910Testing for orientation issues3 June 2017 01:13:36
Gs3007Data Quality issue. Your data provider is reporting heterozygosity on the Y chromosome.23 October 2016 09:50:25
Gs3037WeGene quality control issues.8 June 2016 05:40:37
Gs306Bad6.5Poor metabolizer of fluoropyrimidines (e.g. 5-fluorouracil, capecitabine or tegafur).25 May 2017 00:56:35
Gs2676APOE1/APOE15 November 2016 18:42:06
Gs216Bad62 copies of the APOE-ε4 allele22 July 2017 03:02:57
Gs228Bad6Sickle cell affected3 June 2017 01:37:39
Gs312Bad5.5Intermediate metabolizer of fluoropyrimidines (such as 5-fluorouracil and capecitabine).25 May 2017 01:02:36
Gs121Bad5DR3/4-DQ8 individual at high risk for type-1 diabetes21 October 2011 06:04:16
Gs305Bad5Likely carrier of one PiS and one PiZ Alpha-1 Antitrypsin (SERPINA1) alleles; A1AT deficiency29 April 2017 17:17:29
... further results


Most Recently Active

 ReputeMagnitudeSummaryModification date
"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
Gs230Bad1.5Possible Alzheimer's disease-related haplotype23 August 2017 13:25:14
Gs236Bad1.6Alzheimer's disease-related haplotype23 August 2017 13:24:37
Gs2832.1claimed to lose 2.5x as much weight on a lower carb diet23 August 2017 13:20:11
Gs2665Data Quality Warning12 August 2017 06:53:38
Gs141Bad3.52x risk of Alzheimer's disease22 July 2017 03:04:47
Gs216Bad62 copies of the APOE-ε4 allele22 July 2017 03:02:57
Gs2383.2Red hair2 July 2017 15:33:55
Gs2413Lighter green, brown or hazel eye color11 June 2017 21:59:55
Gs291Good3Lower heart attack risk than average6 June 2017 23:30:26
Gs294Bad2Iron overload may contribute to increased risk of Alzheimer's disease6 June 2017 03:27:07
... further results


You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.