Gallstone disease

Gallstone disease, formally known as cholelithiasis, occurs when gallstones obstruct the bile duct. With an overall prevalence of up to 20% in adults, gallstone disease is one of the most frequent and economically relevant health problems of industrialized countries.Wikipedia

SNPs associated with risk for gallstone disease include:

• rs11887534, in the ABCG8 gene, accounting for perhaps 10% of population risk;
• rs4994, in the ADRB3 gene
• rs440446, in the APOE gene
• rs3758650, in the CDHR5 gene
• Rs6742078, in the UGT1A1 gene [PMID 23753274]