|(C;C)||2||2x higher risk in certain women for cardiac events; associated with elite endurance performance in men|
|(C;T)||2x higher risk in certain women for cardiac events; associated with elite endurance performance in men|
In a study of 600+ women initially referred for coronary angiography and then followed for 6 years, during which time 115 experienced a heart problem, rs4994(C) individuals were calculated to be at higher risk (adjusted hazard ratio 2.10, CI: 1.05-4.24). This risk was due to subtle increases in risk for all of the individual endpoints, and was only seen in women without obstructive coronary artery disease.[PMID 18331634]
[PMID 19553224] Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance
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|CLNSRC||OMIM Allelic Variant UniProtKB (protein)|
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