DYRK1B
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EntrezGene | 9149 |
| PheGenI | 9149 |
| VariationViewer | 9149 |
| ClinVar | DYRK1B |
| GeneCards | DYRK1B |
| dbSNP | 9149 |
| Diseases | DYRK1B |
| SADR | 9149 |
| HugeNav | 9149 |
| wikipedia | DYRK1B |
| DYRK1B | |
| gopubmed | DYRK1B |
| EVS | DYRK1B |
| HEFalMp | DYRK1B |
| MyGene2 | DYRK1B |
| 23andMe | DYRK1B |
| UniProt | Q9Y463 |
| Ensembl | ENSG00000105204 |
| OMIM | 604556 |
| # SNPs | 2 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs367643250 | 4 | 39,830,443 | metabolic syndrome (type-2 diabetes, coronary artery disease, obesity) |
| rs587777380 | 0 | 39,830,478 |
The DYRK1B gene on chromosome 19 encodes the enzyme Dual specificity tyrosine-phosphorylation-regulated kinase 1B.Wikipedia
Genome-wide association studies have linked SNPs in DYRK1B to type-2 diabetes and traits associated with metabolic syndrome, and more recently, several quite rare variants (in particular, rs367643250 and one SNP lacking a dbSNP rsid) have been directly linked to an inherited form of metabolic syndrome, with implications for drug development across diabetes, heart disease, and obesity.[PMID 24827035]
