Rs8702

From SNPedia

Jump to: navigation, search
is asnp
is mentioned by
dbSNPrs8702
hapmaprs8702
hgdprs8702
ensemblrs8702
gopubmedrs8702
scholarrs8702
googlers8702
pharmgkbrs8702
hgvbaseg2prs8702
medrefsnprs8702
23andMers8702
SNP Nexus

GeneKLC1
Chromosome14
Orientationminus
Position103222105
GenotypeEffect
rs8702(G;G)0.2x risk for MS
rs8702(C;G)?
rs8702(C;C)average


Genotypes Magnitude Summary
Rs8702(C;C) average
Rs8702(C;G) ?
Rs8702(G;G) 0.2x risk for MS

SNP rs8702, located in the KLC1 gene, has been reported to have a protective effect against the occurence of multiple sclerosis. Specifically, the odds of a rs8702(G;G) individual - as oriented to the dbSNP entry, not as published - are reported to be 0.21 (CI: 0.018 - 0.88). [PMID 17999208]

A study of ~800 Swedish patients with Alzheimer's disease did not find an association to rs8702 independently, however, rs8702 interacted with ApoE4 carrier status in AD (p=0.006).[PMID 17611642]

? (C;C) (C;G) (G;G)


[PMID 19911314] Kinesin Light Chain 1 Gene Haplotypes in Three Conformational Diseases