Rs713598

rs713598 is one of three SNPs that form the main haplotypes behind the ability to perceive as bitter the taste of the compound phenylthiocarbamide (PTC) and similar molecules in foods (like cabbage and raw broccoli) or drinks (like coffee and dark beers).

The rs713598(G) allele, in the orientation shown in dbSNP, is the "tasting" allele, and it is dominant to the "non-tasting" allele rs713598(C), so having one copy is enough to have the bitter tasting ability. If you are a "taster", you're also likely to carry at least one rs10246939(C) and one rs1726866(C) allele since, along with rs713598(G), these three SNPs form the most common tasting haplotype. If you lack these alleles, you're quite likely (~80%) to be a non-taster of bitterness, meaning that foods that may taste bitter to others taste far less bitter to you.[PMID 12595690]

GWAS snp
PMID	[PMID 20675712]
Trait
Title	The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12
Risk Allele
P-val	2E-104
Odds Ratio	None None