Rs1726866

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is asnp
is mentioned by
dbSNPrs1726866
hapmaprs1726866
hgdprs1726866
ensemblrs1726866
gopubmedrs1726866
scholarrs1726866
googlers1726866
pharmgkbrs1726866
hgvbaseg2prs1726866
medrefsnprs1726866
23andMers1726866
SNP Nexus

GeneTAS2R38
Chromosome7
Orientationminus
Position141319173
GenotypeEffect
rs1726866(C;C)can taste bitter
rs1726866(C;T)can taste bitter
rs1726866(T;T)possible unable to taste bitter


Genotypes Magnitude Summary
Rs1726866(C;C) 0.10.1 can taste bitter
Rs1726866(C;T) 0.10.1 can taste bitter
Rs1726866(T;T) 1.11.1 possible unable to taste bitter
rs1726866 is one of three SNPs that form the main haplotypes behind the ability to perceive as bitter the taste of the compound phenylthiocarbamide (PTC) and similar molecules in foods (like cabbage and raw broccoli) or drinks (like coffee and dark beers).

The rs1726866(C) allele is the "tasting" allele, and it is dominant to the "non-tasting" allele rs1726866(T), so having one copy is enough to have the bitter tasting ability. If you are a "taster", you're also likely to carry at least one rs713598(G) and one rs10246939(C) allele since, along with rs1726866(C), these three SNPs form the most common tasting haplotype. If you lack these alleles, you're quite likely (~80%) to be a non-taster of bitterness, meaning that foods that may taste bitter to others taste far less bitter to you.[PMID 12595690]

Neighborrs10246939
Distance101
? (C;C) (C;T) (T;T)
Related to TASTE RECEPTOR, TYPE 2, MEMBER 38; TAS2R38 according to omim 607751. See also