From SNPedia
[
PMID 18839428]
colorectal cancer rs10505477 and
rs6983267 yielded allelic p-values of 1.42 x 10(-7) and 2.57 x 10(-7), respectively with OR=1.50 (95% CI: 1.29-1.75). Risk region was delineated by SNPs rs10505477 and
rs7014346 and comprised 17 kb
| ? | (A;A) (A;G) (G;G) |
|---|
 |
| GWAS
|
| SNP
| rs7014346
|
| PubMedID
| [PMID 18372901]
|
| Condition
| Colorectal cancer
|
| Gene
| POU5FIP1, HsG57825, DQ515897
|
| Risk Allele
| A
|
| pValue
| 9.00E-026
|
| OR
| 1.19
|
| 95% CI
| 1.15-1.23
|
Related to COLORECTAL CANCER, SUSCEPTIBILITY TO, 2; CRCS2
according to
omim 611469. See
also
| PharmGKB | PA162356763 |
| Name | |
| Annotation | GWAS Results: Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 (Initial Sample Size: 981 cases, 1,002 controls; Replication Sample Size: 16,476 cases, 15,351 controls; Risk Allele: rs7014346-A). |
| Gene | POU5F1P1 |
| Featue | |
| Evidence | PubMed ID:18372901; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Colorectal Neoplasms |
| Curation Level | Non-Curated |
