Rs10505477

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is asnp
is mentioned by
dbSNPrs10505477
hapmaprs10505477
hgdprs10505477
ensemblrs10505477
gopubmedrs10505477
scholarrs10505477
googlers10505477
pharmgkbrs10505477
hgvbaseg2prs10505477
medrefsnprs10505477
23andMers10505477
SNP Nexus

Chromosome8
Orientationminus
Position128476624
GenotypeEffect
rs10505477(C;C)*?
rs10505477(C;T)*?
rs10505477(T;T)*?


[PMID 18056436] Associated with risk of colorectal cancer; (P = 0.005)

[PMID 18839428] colorectal cancer rs10505477 and rs6983267 yielded allelic p-values of 1.42 x 10(-7) and 2.57 x 10(-7), respectively with OR=1.50 (95% CI: 1.29-1.75). Risk region was delineated by SNPs rs10505477 and rs7014346 and comprised 17 kb

? (C;C) (C;T) (T;T)
GWAS
SNP rs10505477
PubMedID [PMID 17618283]
Condition Colorectal cancer
Gene ORF DQ515897
Risk Allele A
pValue 3.00E-011
OR 1.17
95% CI 1.12-1.23


Related to COLORECTAL CANCER, SUSCEPTIBILITY TO, 2; CRCS2 according to omim 611469. See also


PharmGKBPA162356669
Name
AnnotationGWAS Results: Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 (Initial Sample Size: 1,257 cases, 1,336 controls; Replication Sample Size: 6,223 cases, 6,443 controls; Risk Allele: rs10505477-A).
Gene-
Featue
EvidencePubMed ID:17618283; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesColorectal Neoplasms
Curation LevelNon-Curated