Rs6837793

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Orientationplus
Geno Mag Summary
(A;A) normal
(A;G) more likely to gain weight if taking risperidone
(G;G) more likely to gain weight if taking risperidone
ReferenceGRCh38 38.1/141
Chromosome4
Position163335583
GeneNPY1R
is asnp
is mentioned by
dbSNPrs6837793
Exacrs6837793
PheGenIrs6837793
nextbiors6837793
hapmaprs6837793
1000 genomesrs6837793
hgdprs6837793
ensemblrs6837793
gopubmedrs6837793
geneviewrs6837793
scholarrs6837793
googlers6837793
pharmgkbrs6837793
gwascentralrs6837793
openSNPrs6837793
23andMers6837793
23andMe allrs6837793
SNP Nexus

SNPshotrs6837793
SNPdbers6837793
MSV3drs6837793
GMAF0.1148
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs6837793 is a SNP associated with the NPY5 receptor gene, located in the single promoter region likely to be co-regulating the Y1 and Y5 receptor genes.

In a study of 101 mostly Caucasian patients prescribed the atypical antipsychotic risperidone, carriers of a rs6837793(G) allele were more likely to gain significant weight compared to rs6837793(A;A) carriers, as assessed by physiogenomic analysis of corresponding weight profiles. Two other SNPs, rs8179183 and rs705381, were also significantly associated with weight profiles in these patients.[PMID 17199131]


[PMID 18254975OA-icon.png] Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat.


[PMID 18828811OA-icon.png] Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.