Rs683395

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is asnp
is mentioned by
dbSNPrs683395
nextbiors683395
hapmaprs683395
1000 genomesrs683395
hgdprs683395
ensemblrs683395
gopubmedrs683395
scholarrs683395
googlers683395
pharmgkbrs683395
gwascentralrs683395
openSNPrs683395
23andMers683395
23andMe allrs683395
SNP Nexus

SNPshotrs683395
SNPdbers683395
MSV3drs683395
GeneLAMP3
Chromosome3
Orientationminus
Position182869818
ReferenceGRCh37 37.1/131
Max Magnitude0
Geno Mag Summary
(A;A) 0
(C;C) 1.3x risk
(C;T) 1.5x risk
(T;T) 0 normal
? (C;C) (C;T) (T;T) 28
rs683395 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.47 (CI 1.26-1.71), and for homozygotes, 1.3 (CI 0.69-2.46). [PMID 17554300]

GWAS
SNP rs683395
PubMedID [PMID 17554300]
Condition Bipolar disorder
Gene NR
Risk Allele G
pValue 5.00E-006
OR 1.47
95% CI 1.26-1.71


PharmGKBPA162356655
Name
AnnotationGWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,868 cases, 2,938 controls; Replication Sample Size: NR; Risk Allele: rs683395-G). This variant is associated with bipolar disorder.
GeneLAMP3
Featue
EvidencePubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesBipolar Disorder
Curation LevelNon-Curated
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