From SNPedia
rs4489954, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.69 (CI: 0.69-0.82) for the (T) minor allele. [PMID 17637780]
| ? | (G;G) (G;T) (T;T) |
|---|
 |
[PMID 19223043] Exploring the genetic link between RLS and ADHD
| PharmGKB | PA162355631 |
| Name | |
| Annotation | In replicated GWAS case-control studies of Caucasian(European and French-Canadian) familial and sporadic RLS, the G allele of rs4489954 was significantly associated with Restless Legs Syndrome. |
| Gene | MAP2K5 |
| Featue | |
| Evidence | PubMed ID:17637780 |
| Drugs | |
| Diseases | Restless Legs Syndrome |
| Curation Level | Curated |
