Rs3761218

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is asnp
is mentioned by
dbSNPrs3761218
hapmaprs3761218
hgdprs3761218
ensemblrs3761218
gopubmedrs3761218
scholarrs3761218
googlers3761218
pharmgkbrs3761218
hgvbaseg2prs3761218
medrefsnprs3761218
23andMers3761218
SNP Nexus

GeneCDC25B
Chromosome20
Orientationplus
Position3724174
GenotypeEffect
rs3761218(C;C)1.3x risk
rs3761218(C;T)normal
rs3761218(T;T)normal


Genotypes Magnitude Summary
Rs3761218(A;G) 00
Rs3761218(C;C) 1.3x risk
Rs3761218(C;T) 00 normal
Rs3761218(G;G) 00
Rs3761218(T;T) normal
rs3761218 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 0.97 (CI 0.81-1.15), and for homozygotes, 1.31 (CI 1.09-1.57). [PMID 17554300]

? (C;C) (C;T) (T;T)
GWAS
SNP rs3761218
PubMedID [PMID 17554300]
Condition Bipolar disorder
Gene NR
Risk Allele C
pValue 7.00E-006
OR 1.03
95% CI 1.15-1.23


PharmGKBPA162356652
Name
AnnotationGWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,868 cases, 2,938 controls; Replication Sample Size: NR; Risk Allele: rs3761218-C). This variant is associated with bipolar disorder.
GeneCDC25B, CENPB
Featue
EvidencePubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesBipolar Disorder
Curation LevelNon-Curated