Rs3761218

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is asnp
is mentioned by
dbSNPrs3761218
nextbiors3761218
hapmaprs3761218
1000 genomesrs3761218
hgdprs3761218
ensemblrs3761218
gopubmedrs3761218
scholarrs3761218
googlers3761218
pharmgkbrs3761218
gwascentralrs3761218
openSNPrs3761218
23andMers3761218
23andMe allrs3761218
SNP Nexus

SNPshotrs3761218
SNPdbers3761218
MSV3drs3761218
GeneCDC25B
Chromosome20
Orientationplus
Position3776175
ReferenceGRCh37 37.1/131
Max Magnitude0
Geno Mag Summary
(A;G) 0
(C;C) 1.3x risk
(C;T) 0 normal
(G;G) 0
(T;T) normal
? (C;C) (C;T) (T;T) 28
rs3761218 has been reported in a large study to be associated with bipolar disorder.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 0.97 (CI 0.81-1.15), and for homozygotes, 1.31 (CI 1.09-1.57). [PMID 17554300]

GWAS
SNP rs3761218
PubMedID [PMID 17554300]
Condition Bipolar disorder
Gene NR
Risk Allele C
pValue 7.00E-006
OR 1.03
95% CI 1.15-1.23


PharmGKBPA162356652
Name
AnnotationGWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,868 cases, 2,938 controls; Replication Sample Size: NR; Risk Allele: rs3761218-C). This variant is associated with bipolar disorder.
GeneCENPB, CDC25B
Featue
EvidencePubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
Drugs
DiseasesBipolar Disorder
Curation LevelNon-Curated
GWAS snp
PMID [PMID 21254220]
Trait
Title Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
Risk Allele
P-val 0.000001
Odds Ratio None None
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