From SNPedia
rs3129934 is a SNP near the HLA-class II region that may be associated with several autoimmune diseases.
In a study of two cohorts (Spanish and American multiple sclerosis patients, each numbering several hundred), rs3129934 was the SNP most associated with increased risk for multiple sclerosis. The odds ratio was 3.3 (CI: 2.3 - 4.9, p = 9 x 10e-11). Seven other SNPs were also identified in this study as associated with increased risk for MS.[PMID 18941528]
[PMID 17554260] associated with type-1 diabetes
| ? | (C;C) (C;T) (T;T) |
|---|
 |
| PharmGKB | PA164740797 |
| Name | |
| Annotation | GWAS results: Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms. (Initial Sample Size: 242 cases, 242 controls; Replication Sample Size: 375 cases, 375 controls); (Region: 6p21.32; Reported Gene(s): HLA-DRB1; Risk Allele: rs3129934-T); (p-value= 0.00000000009).This variant is associated with Multiple sclerosis. |
| Gene | C6orf10 |
| Featue | |
| Evidence | PubMed ID:18941528; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Multiple Sclerosis |
| Curation Level | Non-Curated |
