Rs2297508
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs2297508 |
| hapmap | rs2297508 |
| hgdp | rs2297508 |
| ensembl | rs2297508 |
| gopubmed | rs2297508 |
| scholar | rs2297508 |
| rs2297508 | |
| pharmgkb | rs2297508 |
| hgvbaseg2p | rs2297508 |
| medrefsnp | rs2297508 |
| 23andMe | rs2297508 |
| SNP Nexus |
| Gene | SREBF1 |
| Chromosome | 17 |
| Orientation | minus |
| Position | 17656041 |
| Genotype | Effect |
|---|---|
| rs2297508(C;C) | normal |
| rs2297508(C;G) | 1.08x increased risk for T2D |
| rs2297508(G;G) | 1.08x increased risk for T2D |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs2297508(C;C) | normal | |
| Rs2297508(C;G) | 1.08x increased risk for T2D | |
| Rs2297508(G;G) | 1.08x increased risk for T2D |
A study of ~2,000 Caucasian patients (and 10,000+ controls) led to an odds ratio of 1.17 (CI: 1.05-1.30, p=0.003) for the minor (risk) allele, rs2297508(C). A meta-analysis included other published studies concluded the odds ratio was 1.08 (CI: 1.03-1.14, p=0.001).[PMID 18192539]
[PMID 18692268] type-2 diabetes rs2297508(C) and rs11868035(C)
| ? | (C;C) (C;G) (G;G) |
|---|---|
|
| |
| Neighbor | rs11868035 |
| Distance | 216 |
