From SNPedia
rs1800693 is a SNP in the tumor necrosis factor receptor superfamily, member 1A
TNFRSF1A gene.
A large study (~5,000 patients) found two SNPs in the TNFRSF1A gene that each (independently) increase risk for multiple sclerosis, rs1800693 and rs4149584. This SNP, rs1800693, is more common but increases risk less; the odds ratio is reported as 1.2 (CI: 1.10-1.31, p=1.6x10(-11)).10.1038/ng.401
| GWAS snp
|
| PMID
| [PMID 19525953]
|
| Trait
| Multiple sclerosis
|
| Title
| Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
|
| Risk Allele
| C
|
| P-val
| 2E-11
|
| Odds Ratio
| 1.20 [1.10-1.31]
|
| ? | (A;A) (A;G) (G;G) |
 |