Rs17810546

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Orientationplus
is asnp
is mentioned by
dbSNPrs17810546
PheGenIrs17810546
hapmaprs17810546
1000 genomesrs17810546
hgdprs17810546
ensemblrs17810546
gopubmedrs17810546
geneviewrs17810546
scholarrs17810546
googlers17810546
pharmgkbrs17810546
gwascentralrs17810546
openSNPrs17810546
23andMers17810546
23andMe allrs17810546
SNP Nexus

SNPshotrs17810546
SNPdbers17810546
MSV3drs17810546
GeneIL12A-AS1
Chromosome3
Orientationplus
GMAF0.05096
Position159947262
ReferenceGRCh38 38.1/141
Max Magnitude0
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs17810546(A;G)
Make rs17810546(G;G)
? (A;A) (A;G) (G;G) 28
GWAS
SNP rs17810546
PubMedID [PMID 18311140OA-icon.png]
Condition Celiac disease
Gene IL12A, SCHIP1
Risk Allele G
pValue 1.00E-009
OR 1.35
95% CI 1.23-1.49


OMIM612008
DescCELIAC DISEASE, SUSCEPTIBILITY TO, 10; CELIAC10
Variant
Relatedalso


GWAS snp
PMID [PMID 20190752OA-icon.png]
Trait Celiac disease
Title Multiple common variants for celiac disease influencing immune gene expression
Risk Allele G
P-val 4E-28
Odds Ratio 1.36 [1.29-1.44]
OMIM212750
Desc
Variant
Relatedalso
[PMID 22087237OA-icon.png] Improving the estimation of celiac disease sibling risk by non-HLA genes


[PMID 18713140OA-icon.png] Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease.


[PMID 18853133OA-icon.png] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.


[PMID 19073967OA-icon.png] Shared and distinct genetic variants in type 1 diabetes and celiac disease.


[PMID 19458352OA-icon.png] Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.


[PMID 19468064OA-icon.png] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.


[PMID 20647273OA-icon.png] Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.


GET Evidence
rs17810546
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.0234375
summary



GWAS snp
PMID [PMID 23291587OA-icon.png]
Trait Behcet's disease
Title Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.
Risk Allele A
P-val 6E-7
Odds Ratio 1.55 [1.30-1.85]