Rs17221417
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs17221417 |
| hapmap | rs17221417 |
| hgdp | rs17221417 |
| ensembl | rs17221417 |
| gopubmed | rs17221417 |
| scholar | rs17221417 |
| rs17221417 | |
| pharmgkb | rs17221417 |
| hgvbaseg2p | rs17221417 |
| medrefsnp | rs17221417 |
| 23andMe | rs17221417 |
| SNP Nexus |
| Gene | NOD2 |
| Chromosome | 16 |
| Orientation | plus |
| Position | 49297082 |
| Genotype | Effect |
|---|---|
| rs17221417(G;G) | 1.9x risk |
| rs17221417(C;G) | 1.3x risk |
| rs17221417(C;C) | normal |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs17221417(C;C) | normal | |
| Rs17221417(C;G) | 1.3x risk | |
| Rs17221417(G;G) | 1.9x risk |
rs17221417 has been reported in a large study to be associated with Crohn's disease.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.29 (CI 1.13-1.46), and for homozygotes, 1.92 (CI 1.58-2.34). [PMID 17554300]
| ? | (C;C) (C;G) (G;G) |
|---|---|
|
| |
Related to NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN PROTEIN 2; NOD2
according to omim 605956. See also
