Rs1329428

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Gene

Chromosome

1

minus

Position

196702810

Reference

GRCh37 37.1/131

2.1

Geno	Mag	Summary
(A;A)	0	normal
(A;G)		?
(G;G)	2.1	2x increased risk for macular degeneration

?	(A;A) (A;G) (G;G)	28

Significant associations were detected for AMD with rs3753394 rs800292 rs1329428

A haplotype of rs1061170 rs3753394 rs800292 rs1329428 (TGTC) was found to confer a significantly increased likelihood of exudative AMD

CFH variations appear to contribute to ARMD in Caucasians, but not in Japanese [PMID 16710702]

GWAS snp
PMID	[PMID 20861866]
Trait
Title	Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration
Risk Allele
P-val	3E-64
Odds Ratio	2.78 [NR]