Rs13015714

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Orientationplus
is asnp
is mentioned by
dbSNPrs13015714
PheGenIrs13015714
nextbiors13015714
hapmaprs13015714
1000 genomesrs13015714
hgdprs13015714
ensemblrs13015714
gopubmedrs13015714
geneviewrs13015714
scholarrs13015714
googlers13015714
pharmgkbrs13015714
gwascentralrs13015714
openSNPrs13015714
23andMers13015714
23andMe allrs13015714
SNP Nexus

SNPshotrs13015714
SNPdbers13015714
MSV3drs13015714
GeneIL18R1
Chromosome2
Orientationplus
GMAF0.2695
Position102355405
ReferenceGRCh38 38.1/141
Max Magnitude
Make rs13015714(G;G)
Make rs13015714(G;T)
Make rs13015714(T;T)
? (G;G) (G;T) (T;T) 28
GWAS
SNP rs13015714
PubMedID [PMID 18311140OA-icon.png]
Condition Celiac disease
Gene IL1RL1,IL18R1,IL18RAP, SLC9A4
Risk Allele C
pValue 4.00E-009
OR 1.28
95% CI 1.18-1.39


OMIM612006
DescCELIAC DISEASE, SUSCEPTIBILITY TO, 8; CELIAC8
Variant
Relatedalso

[PMID 19693089] Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort



[PMID 18853133OA-icon.png] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.


[PMID 19103669] Association study of the IL18RAP locus in three European populations with coeliac disease.


[PMID 19468064OA-icon.png] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.


GET Evidence
rs13015714
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.841667
summary



GWAS snp
PMID [PMID 23042114]
Trait Atopic dermatitis
Title Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Risk Allele G
P-val 8E-18
Odds Ratio 1.27 [1.20-1.34]