From SNPedia
rs1265181 is a SNP in the HLA region of chromosome 6.
A large study (>6,000 Chinese psoriasis patients and an equal number of controls) found a highly significant association between the minor rs1265181(G) allele and risk for psoriasis.[PMID 19169255] A proxy for this allele is rs1265159(A).
See also:
spittoon psoriasis
| ? | (C;C) (C;G) (G;G) |
|---|
 |
| GWAS snp
|
| PMID
| [PMID 19169255]
|
| Trait
| Psoriasis
|
| Title
| Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
|
| Risk Allele
|
|
| P-val
| NS
|
| Odds Ratio
| 22.62 None
|
| PharmGKB | PA164740046 |
| Name | |
| Annotation | GWAS results: Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. (Initial Sample Size: 1,139 Chinese cases, 1,132 Chinese controls; Replication Sample Size: 5,721 Chinese cases, 7,340 Chinese controls); (Region: 6p21.33; Reported Gene(s): MHC; Risk Allele: rs1265181-?); (p-value= NS).This variant is associated with Psoriasis. |
| Gene | HCG27 |
| Featue | |
| Evidence | PubMed ID:19169255; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Psoriasis |
| Curation Level | Non-Curated |
