Rs12243326
From SNPedia
| Orientation | plus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12243326 |
| PheGenI | rs12243326 |
| nextbio | rs12243326 |
| hapmap | rs12243326 |
| 1000 genomes | rs12243326 |
| hgdp | rs12243326 |
| ensembl | rs12243326 |
| gopubmed | rs12243326 |
| geneview | rs12243326 |
| scholar | rs12243326 |
| rs12243326 | |
| pharmgkb | rs12243326 |
| gwascentral | rs12243326 |
| openSNP | rs12243326 |
| 23andMe | rs12243326 |
| 23andMe all | rs12243326 |
| SNP Nexus | |
| SNPshot | rs12243326 |
| SNPdbe | rs12243326 |
| MSV3d | rs12243326 |
| Gene | TCF7L2 |
| Chromosome | 10 |
| Orientation | plus |
| GMAF | 0.1973 |
| Position | 114788815 |
| Reference | GRCh37 37.1/131 |
| Max Magnitude |
| Make rs12243326(C;C) |
| Make rs12243326(C;T) |
| Make rs12243326(T;T) |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
| GWAS snp | |
|---|---|
| PMID | [PMID 20081857] |
| Trait | Two-hour glucose challenge |
| Title | Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge |
| Risk Allele | C |
| P-val | 1E-7 |
| Odds Ratio | 0.08 [0.06-0.10] mmol/L increase |
[PMID 17934151] A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.
| GET Evidence | |
|---|---|
| rs12243326 | |
| aa_change | |
| aa_change_short | |
| impact | pharmacogenetic |
| qualified_impact | Insufficiently evaluated pharmacogenetic |
| overall_frequency | 0.234375 |
| summary | |
