Rs12243326

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Orientationplus
Make rs12243326(C;C)
Make rs12243326(C;T)
Make rs12243326(T;T)
ReferenceGRCh37 37.1/131
Chromosome10
Position114788815
GeneTCF7L2
is asnp
is mentioned by
dbSNPrs12243326
Exacrs12243326
PheGenIrs12243326
nextbiors12243326
hapmaprs12243326
1000 genomesrs12243326
hgdprs12243326
ensemblrs12243326
gopubmedrs12243326
geneviewrs12243326
scholarrs12243326
googlers12243326
pharmgkbrs12243326
gwascentralrs12243326
openSNPrs12243326
23andMers12243326
23andMe allrs12243326
SNP Nexus

SNPshotrs12243326
SNPdbers12243326
MSV3drs12243326
GMAF0.1974
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 20081857OA-icon.png]
Trait Two-hour glucose challenge
Title Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Risk Allele C
P-val 1E-7
Odds Ratio 0.08 [0.06-0.10] mmol/L increase



[PMID 17934151] A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.


GET Evidence
rs12243326
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.234375
summary



[PMID 24157263] Polymorphisms of Transcription Factor-7-Like 2 (TCF7L2) gene in Tunisian women with polycystic ovaries syndrome (PCOS)


[PMID 23107111] Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects.


[PMID 23142382] Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Tunisian Arab subjects.