Rs1026732

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is asnp
is mentioned by
dbSNPrs1026732
hapmaprs1026732
hgdprs1026732
ensemblrs1026732
gopubmedrs1026732
scholarrs1026732
googlers1026732
pharmgkbrs1026732
hgvbaseg2prs1026732
medrefsnprs1026732
23andMers1026732
SNP Nexus

GeneMAP2K5
Chromosome15
Orientationplus
Position65882139
GenotypeEffect
rs1026732(A;A)<0.70x risk for restless legs
rs1026732(A;G)0.70x risk for restless legs
rs1026732(G;G)common


Genotypes Magnitude Summary
Rs1026732(A;A) <0.70x risk for restless legs
Rs1026732(A;G) 0.70x risk for restless legs
Rs1026732(C;C) 00
Rs1026732(G;G) 00 common
rs1026732, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.70 (CI: 0.59-0.82) for the (A) minor allele. [PMID 17637780]
? (A;A) (A;G) (G;G)
PharmGKBPA162355633
Name
AnnotationIn replicated GWAS case-control studies of Caucasian(European and French-Canadian) familial and sporadic RLS, the G allele of rs1026732 was significantly associated with Restless Legs Syndrome.
GeneMAP2K5
Featue
EvidencePubMed ID:17637780
Drugs
DiseasesRestless Legs Syndrome
Curation LevelCurated