Rs10239794

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is asnp
is mentioned by
dbSNPrs10239794
hapmaprs10239794
hgdprs10239794
ensemblrs10239794
gopubmedrs10239794
scholarrs10239794
googlers10239794
pharmgkbrs10239794
hgvbaseg2prs10239794
medrefsnprs10239794
23andMers10239794
SNP Nexus

GeneDPP6
Chromosome7
Orientationplus
Position153836826
GenotypeEffect
rs10239794(C;C)average
rs10239794(C;T)1.3x risk for ALS
rs10239794(T;T)>1.3x risk for ALS


Genotypes Magnitude Summary
Rs10239794(C;C) average
Rs10239794(C;T) 1.3x risk for ALS
Rs10239794(T;T) 00 >1.3x risk for ALS
rs10239794, a SNP in the region of the DPP6 gene on chromosome 7, has been associated with the sporadic form of ALS (Lou Gehrig's disease) in a study of 1000+ European patients. The odds ratio for the risk allele rs10239794(C) is 1.30 (CI: 1.18 - 1.43). [PMID 18084291]

A "CC" haplotype for this SNP and that of it's neighbor rs10260404 is also highly (statistically; p=10e-9) associated with ALS. [PMID 18084291]

? (C;C) (C;T) (T;T)
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