DPP6
From SNPedia
| is a | gene |
| is | mentioned by |
| Full name | dipeptidyl-peptidase 6 |
| EntrezGene | 1804 |
| PheGenI | 1804 |
| VariationViewer | 1804 |
| ClinVar | DPP6 |
| GeneCards | DPP6 |
| dbSNP | 1804 |
| Diseases | DPP6 |
| SADR | 1804 |
| HugeNav | 1804 |
| wikipedia | DPP6 |
| DPP6 | |
| gopubmed | DPP6 |
| EVS | DPP6 |
| HEFalMp | DPP6 |
| MyGene2 | DPP6 |
| 23andMe | DPP6 |
| UniProt | P42658 |
| Ensembl | ENSG00000130226 |
| OMIM | 126141 |
| # SNPs | 17 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs10239794 | 1 | 154,508,809 | |
| rs10260404 | 2 | 154,513,713 | |
| rs12534701 | 0 | 154,889,200 | |
| rs12666280 | 0 | 154,717,614 | |
| rs12671878 | 0 | 153,861,864 | |
| rs2110267 | 0 | 153,838,604 | |
| rs2192271 | 0 | 153,852,211 | |
| rs3807218 | 0 | 154,669,402 | |
| rs38989 | 0 | 153,881,331 | |
| rs606231226 | 0 | 154,305,155 | |
| rs6464375 | 0 | 153,928,758 | |
| rs6947495 | 0 | 153,855,979 | |
| rs6977820 | 0 | 154,374,935 | |
| rs71534169 | 0 | 154,801,156 | |
| rs758316 | 0 | 153,934,563 | |
| rs7779540 | 0 | 153,925,577 | |
| rs786205143 | 0 | 154,794,095 |
Two SNPs in the DPP6 region of ch 7 have been associated with ALS:
Each shows independent increased risk for ALS, and together they form a haplotype of quite significant (statistically; 10e-9) risk though the overall odds ratio is still relatively low. [PMID 18084291] Dec07 Press Release
