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rs3825776

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1 Normal risk for ALS
(A;G) 1.5 1.3x increased risk for ALS
(G;G) 2 >1.3x increased risk for ALS
(T;T) 0
ReferenceGRCh38 38.1/141
Chromosome15
Position58454631
GeneLIPC, LIPC-AS1
is asnp
is mentioned by
dbSNPrs3825776
dbSNP (old)rs3825776
ClinGenrs3825776
ebirs3825776
HLIrs3825776
Exacrs3825776
Gnomadrs3825776
Varsomers3825776
LitVarrs3825776
Maprs3825776
PheGenIrs3825776
Biobankrs3825776
1000 genomesrs3825776
hgdprs3825776
ensemblrs3825776
gopubmedrs3825776
geneviewrs3825776
scholarrs3825776
googlers3825776
pharmgkbrs3825776
gwascentralrs3825776
openSNPrs3825776
23andMers3825776
23andMe allrs3825776
SNPshotrs3825776
SNPdbers3825776
MSV3drs3825776
GWAS Ctlgrs3825776
GMAF0.4169
Max Magnitude2
? (A;A) (A;G) (G;G) 28

rs3825776, a SNP in the region of the LIPC gene on chromosome 15, has been associated with the sporadic form of ALS (Lou Gehrig's disease) in a study of 1000+ European patients. The odds ratio for the risk allele rs3825776(G) is 1.34 (CI: 1.12 - 1.46). [PMID 18084291]


[PMID 18078817OA-icon.png] Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.