UGT2B17
From SNPedia
| is a | gene |
| is | mentioned by |
| EntrezGene | 7367 |
| PheGenI | 7367 |
| VariationViewer | 7367 |
| ClinVar | UGT2B17 |
| GeneCards | UGT2B17 |
| dbSNP | 7367 |
| Diseases | UGT2B17 |
| SADR | 7367 |
| HugeNav | 7367 |
| wikipedia | UGT2B17 |
| UGT2B17 | |
| gopubmed | UGT2B17 |
| EVS | UGT2B17 |
| HEFalMp | UGT2B17 |
| MyGene2 | UGT2B17 |
| 23andMe | UGT2B17 |
| # SNPs | 8 |
| Max Magnitude | Chromosome position | Summary | |
|---|---|---|---|
| rs10025771 | 0 | 68,539,507 | |
| rs11723091 | 0 | 68,539,752 | |
| rs11938019 | 0 | 68,559,644 | |
| rs13327941 | 0 | 68,556,427 | |
| rs6552182 | 0 | 68,567,230 | |
| rs6857249 | 0 | 68,569,184 | |
| rs7435827 | 0 | 68,549,226 | |
| rs7436338 | 0 | 68,567,561 |
[PMID 19789632] This gene harbors Copy Number Variations which vary significantly among populations.
[PMID 18334593] Deletion of both copies of this gene alters testosterone metabolism making steroid use undetectable.
One type of deletion polymorphism in the UGT2B17 gene lowered urinary testosterone glucuronide levels and that polymorphism allele was found at a "frequency of 29% in Swedes and 78% in Koreans."
It may be possible to detect the deletion by checking the snps below which occur on the Illumina 1M chip.
the 23andMe chip does not test for this.
UGT2B17 has been associated with Prostate cancer [1]
