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From SNPedia

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ReferenceGRCh38 38.1/141
is asnp
is mentioned by
dbSNP (classic)rs4073
1000 genomesrs4073
23andMe allrs4073
GWAS Ctlgrs4073
Max Magnitude0

[PMID 26547713] Polymorphism in the IL-8 Gene Promoter and the Risk of Acne Vulgaris in a Pakistani Population

[PMID 26400525] Association between variants of IL-8 and IL-10 genes, and efficacy of transcatheter arterial chemoembolization and subsequent prognosis in patients with liver cancer

[PMID 26154559OA-icon.png] The genetic variant rs4073 A→T of the Interleukin-8 promoter region is associated with the earlier onset of exudative age-related macular degeneration

[PMID 26135929] A Systematic Review and Meta-Analysis of Three Gene Variants Association with Risk of Prostate Cancer: An Update

[PMID 26047319OA-icon.png] Variation in genes involved in the immune response and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial

[PMID 25521357] Pharmacogenetic interaction analysis of VEGFR-2 and IL-8 polymorphisms in advanced breast cancer patients treated with paclitaxel and bevacizumab

[PMID 25251027] Low IL-8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels

[PMID 25139485] Single-nucleotide polymorphisms in the vascular endothelial growth factor pathway and outcomes of patients treated with first-line cytotoxic chemotherapy combined with bevacizumab for advanced colorectal cancer

[PMID 25000179OA-icon.png] Genetic polymorphisms and sepsis in premature neonates

[PMID 24462138] Association of interleukin 8 with myocardial infarction: Results from the Stockholm Heart Epidemiology Program

[PMID 24072654] Influence of interleukin gene polymorphisms on development of acute pancreatitis: a systematic review and meta-analysis

[PMID 23831257] Association of IL-8 gene polymorphisms with Non Small Cell Lung Cancer in Tunisia: a case control study

[PMID 23545310] Association between -251A>T polymorphism in the interleukin-8 gene and oral cancer risk: A meta-analysis

[PMID 23251429OA-icon.png] Inflammation and immune-related candidate gene associations with acute lung injury susceptibility and severity: a validation study.

[PMID 23086128] Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer

[PMID 22788685] Polymorphisms of pro-inflammatory cytokine genes and the risk for acute suppurative or chronic nonsuppurative apical periodontitis in a Colombian population

[PMID 22727395OA-icon.png] Genetic analysis of the IL8 gene polymorphism (rs4073) in generalized aggressive periodontitis

[PMID 22132000OA-icon.png] The IL1B-511 Polymorphism (rs16944 AA Genotype) Is Increased in Aspirin-Exacerbated Respiratory Disease in Mexican Population

[PMID 22000099OA-icon.png] Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness.

[PMID 21681427] -251 T/A polymorphism of the interleukin-8 gene and cancer risk: a HuGE review and meta-analysis based on 42 case-control studies

[PMID 21649933OA-icon.png] A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode

[PMID 21637534OA-icon.png] Interleukin-8-251T > A, Interleukin-1?-889C > T and Apolipoprotein E polymorphisms in Alzheimer's disease

[PMID 21214373] Polymorphisms of CXCL8 and Its Receptor CXCR2 Contribute to the Development and Progression of Childhood IgA Nephropathy.

[PMID 21188496] Haplotypes in the Interleukin 8 Gene and Their Association with Chronic Periodontitis Susceptibility

[PMID 21091348OA-icon.png] Interleukin-8 gene promoter polymorphism (rs4073) may contribute to chronic periodontitis

[PMID 21042230] Genetic Polymorphisms and Susceptibility to Parenchymal Renal Infection Among Pediatric Patients

[PMID 20811626OA-icon.png] Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

[PMID 20463618OA-icon.png] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.

[PMID 20431935OA-icon.png] Polymorphisms in inflammatory genes, plasma antioxidants, and prostate cancer risk

[PMID 20015396OA-icon.png] Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.

[PMID 19994728] Interleukin-8 T-251A polymorphism was associated with positive anti-p53 antibodies in Uzbekistan population.

[PMID 19842025] Association of Interleukin-8 Gene Polymorphisms and Haplotypes with Oral Lichen Planus in a Chinese Population

[PMID 19390575OA-icon.png] Lung cancer susceptibility model based on age, family history and genetic variants.

[PMID 19364277] Lack of association of a functional polymorphism in the interleukin 8 gene with susceptibility to periodontitis.

[PMID 19356949OA-icon.png] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.

[PMID 19357773OA-icon.png] Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians.

[PMID 19347053OA-icon.png] Analysis of inflammation- and atherosclerosis-related gene polymorphisms in branch retinal vein occlusion.

[PMID 19066394OA-icon.png] Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma.

[PMID 18992148OA-icon.png] Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.

[PMID 18633131OA-icon.png] Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era.

[PMID 18549840OA-icon.png] Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke.

[PMID 17848170OA-icon.png] The chemokine network. II. On how polymorphisms and alternative splicing increase the number of molecular species and configure intricate patterns of disease susceptibility.

[PMID 17356794] Association of common polymorphisms in inflammatory genes with risk of developing cancers of the upper aerodigestive tract.

[PMID 17327408OA-icon.png] Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival.

[PMID 17211588] Lack of association of IL8 gene polymorphisms with familial vesico-ureteral reflux.

[PMID 16820586OA-icon.png] Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.

[PMID 16719905OA-icon.png] Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus.

[PMID 16503988OA-icon.png] Impact of IL8 and IL8-receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections.

[PMID 28993876] IL-8 Gene Variants and Expression in Childhood Asthma.

[PMID 30186498OA-icon.png] Association of cytokine gene polymorphisms with osteoarthritis susceptibility.

[PMID 30275190] IL-8-251T>A (rs4073) Polymorphism Is Associated with Prognosis in Gastric Cancer Patients.

[PMID 30995942OA-icon.png] A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome.